HORDB

ID: hor001248
Uniprot ID: G5EGN5
Protein name: FLP-8
Gene name: flp-8
Organism: Caenorhabditis elegans
Family: FARP (FMRFamide related peptide) family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Caenorhabditis (genus), Peloderinae (subfamily), Rhabditidae (family), Rhabditoidea (superfamily), Rhabditomorpha (infraorder), Rhabditina (suborder), Rhabditida (order), Chromadorea (class), Nematoda (phylum), Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway; GO:0061096 negative regulation of turning behavior involved in mating
GO CC: GO:0005576 extracellular region

Sequence: KNEFIRF
Length: 7(74-80)
Propeptide: MLSGVLFSIFVLAISANASCDVSALTTENEKELGLRICHLEAEMQVVQRALQEVMQQTDVTLYDQEVPVMNKRKNEFIRFGKRSDGMEKRKNEFIRFGKRKNEFIRFGRSDKGLGLDDNDVSSEFFGYTSDVFYL
Signal peptide: MLSGVLFSIFVLAISANA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor001248_AF2.pdb

hor001248_ESM.pdb

Mass:	106030	Formula:	C45H68N12O11
Absent amino acids:	ACDGHLMPQSTVWY	Common amino acids:	F
pI:	9.69	Basic residues:	2
Polar residues:	1	Hydrophobic residues:	3
Hydrophobicity:	-75.71	Boman Index:	-2304
Half-Life:	1.3 hour	Half-Life Yeast:	3 min
Half-Life E.Coli:	2 min	Aliphatic Index	55.71
Instability Index:	857.14	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 20013198
Title: Approaches to Identify Endogenous Peptides in the Soil Nematode Caenorhabditis elegans